Bactrim

Let me start by describing what we’re dealing with here, because Bactrim is one of those agents that’s been around so long it’s almost part of the furniture in infectious disease, but that familiarity can breed a dangerous complacency. It’s not a simple pill. Bactrim, known generically as trimethoprim-sulfamethoxazole (TMP-SMX), is a fixed-dose combination antimicrobial agent. It’s a classic example of sequential double blockade biochemistry we use to hammer certain pathogens.