Zestoretic

Let’s talk about Zestoretic. In my practice, it’s one of those workhorse medications that’s been on the formulary for years, but its utility often gets overlooked in the rush towards newer, flashier agents. It’s not a dietary supplement or a device; it’s a prescription pharmaceutical, a fixed-dose combination (FDC) of two old, well-understood drugs: lisinopril, an ACE inhibitor, and hydrochlorothiazide (HCTZ), a thiazide diuretic. We use it for hypertension, pure and simple, but the elegance is in the combination.