Diclofenac SR

Diclofenac SR, or diclofenac sodium in a sustained-release formulation, is a cornerstone non-steroidal anti-inflammatory drug (NSAID) used globally. It belongs to the phenylacetic acid derivative class and is a potent inhibitor of cyclooxygenase (COX) enzymes, which are central to the inflammatory process. The “SR” designation—Sustained Release—is the critical differentiator from its immediate-release counterparts. This monograph provides a comprehensive, evidence-based review of Diclofenac SR, detailing its pharmacokinetics, therapeutic applications, safety profile, and clinical nuances essential for both prescribing healthcare professionals and informed patients.