Insulin Glargine: Basal Glycemic Control for Diabetes Mellitus - Evidence-Based Review

Product Description: Insulin glargine is a long-acting basal insulin analog used in the management of diabetes mellitus. It is produced using recombinant DNA technology, resulting in a modified insulin molecule that forms a microprecipitate in the subcutaneous tissue after injection. This allows for a slow, consistent release into the bloodstream, providing a relatively flat, peakless pharmacokinetic profile over approximately 24 hours. It is indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.